by member of RAS Valery LUNIN, Head of the Department of Physical Chemistry, Chemical Faculty, M. Lomonosov Moscow State University, Pavel MOROZOV, Dr. Sc. (Medicine), Head of the Clinical Center of the Moscow Medical Academy, Irina KOSHELEVA, Cand. Sc. (Medicine), Head of the Oxygen Therapy Unit, Clinic of Skin and Venereal Diseases, Moscow Medical Academy Ozone therapeutic device UOTA-60 - 01 MEDOZONE. Thin atmospheric layer protecting all that is alive from the harmful exposure of short-wave ultraviolet solar radiation... Fresh odor in the air after storm... These are the most frequent associations linked with ozone. But for the hundreds of thousands of patients in Russia and foreign countries, who experienced the favorable effects of a new therapeutic method-oxygen-ozone therapy (OOT), this word is associated with relief from suffering. стр. 17 Ozonometer for ozone concentration measuring in water solutions. Local application of oxygen-ozone mixture. Ozone is one of allotropic form of oxygen. Its molecule, in contrast to common O2, consists of three atoms, due to which it acquires specific physico-chemical characteristics, responsible for unique biological effects*. During the interactions with living tissues, this highly reactive gas-oxidizer reacts mainly at the site of double carbon bonds (-C=C-) in unsaturated fatty acids and sulfohydryl groups (-SH-) in aromatic amino acids and peptides. It immediately reacts with bio-organic substrates. By contrast, "common" oxygen in such a situation needs assistants, or biocatalyzers, such as enzymes, trace elements. Attempts to apply ozone in medicine were made as long ago as in the mid-19th century; this was due to its oxidative effects, which were obvious. However, ozone therapeutic application became possible only in the second half of the 20th century after the comprehensive studies of O3 were held and its role as a regulator of biological processes at molecular and cellular levels became obvious. Of ... Read more